Holders Liverpool will face Napoli, Salzburg and Genk in the Champions League group stage this season.
Premier League champions Manchester City were drawn alongside Shakhtar Donetsk, Dinamo Zagreb and Atalanta.
Last year’s runners-up Tottenham are in a group with five-time European Cup winners Bayern Munich, plus Olympiakos and Red Star Belgrade.
Chelsea must negotiate a group including 2019 semi-finalists Ajax, Valencia and Lille.
European heavyweights Paris St-Germain and Real Madrid were drawn together in Group A while former winners Barcelona, Borussia Dortmund and Inter Milan will all meet in Group F.
This year’s group stage begins on Tuesday, 17 September while the final is on Saturday, 30 May at the Ataturk Stadium in Istanbul.
Liverpool met Napoli in the group stage of last year’s competition, winning at home and losing the away tie in Italy, before going on to win the tournament for a sixth time.
“Napoli are obviously a very experienced side and their coach Carlo Ancelotti has won the competition,” said manager Jurgen Klopp.
“I will need now to have another, closer look at Genk and Salzburg, but I already know they are very young, very exciting and very fresh, so it will be interesting, 100%.”
It will be the third year in a row Manchester City, who lost in the quarter-final to Spurs last season, will face Shakhtar in the group stage.
“Zagreb and Atalanta are new opponents for us, but both teams play really good football and I think you will see some great games in this group,” City director of football Txiki Begiristain said.
Tottenham reached the European Cup final for the first time last season and forward Son Heung-min said they must “remember and learn from” the campaign.
“Bayern will be special because they are one of the biggest teams in Europe, you’re always excited to play in this competition against these teams,” the South Korea international added.
Group stage draw in full:
Group A: Paris St-Germain, Real Madrid, Club Bruges, Galatasaray
Group B: Bayern Munich, Tottenham, Olympiakos, Red Star Belgrade
Group C: Manchester City, Shakhtar Donetsk, Dinamo Zagreb, Atalanta
Group D: Juventus, Atletico Madrid, Bayer Leverkusen, Lokomotiv Moscow
Group E: Liverpool, Napoli, Salzburg, Genk
Group F: Barcelona, Borussia Dortmund, Inter Milan, Slavia Prague
Group G: Zenit St Petersburg, Benfica, Lyon, RB Leipzig
Group H: Chelsea, Ajax, Valencia, Lille
Please, remember to always like our page and visit our website for updates. You can also download our android mobile app from google playstore